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Key Lab of Stem Cell Biology
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Differential regulation of mRNA stability controls the transient expression of genes encoding Drosophila antimicrobial peptide with distinct immune response Mission.
Wei Y, Xiao Q, Zhang T, Mou Z, You J, Ma WJ.
Nucleic Acids Res. 2009 Oct;37(19):6550-61.

Divergence of exonic splicing elements after gene duplication and the impact on gene structures.
Zhang Z, Zhou L, Wang P, Liu Y, Chen X, Hu L, Kong X.
Genome Biol. 2009 Nov 2;10(11):R120.

Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ.
J Immunol. 2009 Nov 15;183(10):6135-44.

An essential role for RIG-I in toll-like receptor-stimulated phagocytosis.
Kong L, Sun L, Zhang H, Liu Q, Liu Y, Qin L, Shi G, Hu JH, Xu A, Sun YP, Li D, Shi YF, Zang JW, Zhu J, Chen Z, Wang ZG, Ge BX.
Cell Host Microbe. 2009 Aug 20;6(2):150-61.

PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation.
Gao F, Kwon SW, Zhao Y, Jin Y.
J Biol Chem. 2009 Aug 14;284(33):22263-73.

Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells.
Li C, Zhou J, Shi G, Ma Y, Yang Y, Gu J, Yu H, Jin S, Wei Z, Chen F, Jin Y.
Hum Mol Genet. 2009 Nov 15;18(22):4340-9.

Regulatory properties of copolymer I in Th17 differentiation by altering STAT3 phosphorylation.
Chen C, Liu X, Wan B, Zhang JZ.
J Immunol. 2009 Jul 1;183(1):246-53.

Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis.
Zheng W, Li R, Pan H, He D, Xu R, Guo TB, Guo Y, Zhang JZ.
Arthritis Rheum. 2009 Jul;60(7):1957-65.

Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals.
Yin S, Wang P, Deng W, Zheng H, Hu L, Hurst LD, Kong X.
Genome Biol. 2009 Jul 13;10(7):R74.

Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay.
Zhang Z, Xin D, Wang P, Zhou L, Hu L, Kong X, Hurst LD.
BMC Biol. 2009 May 14;7(1):23.

Mir-144 selectively regulates embryonic α-hemoglobin synthesis during primitive erythropoiesis.
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX.
Blood. 2009 Feb 5;113(6):1340-1349.

Critical roles of coactivator p300 in mouse embryonic stem cell differentiation and nanog expression.
Zhong X, Jin Y.
J Biol Chem. 2009 Apr 3;284(14):9168-9175.

The role of CCAAT/enhancer binding protein (C/EBP)-α in osteogenesis of C3H10T1/2 cells induced by BMP-2.
Fan Q, Tang T, Zhang X, Dai K.
J Cell Mol Med. 2009 Aug;13(8B):2489-505.

AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2.
Jiao B, Wu CF, Liang Y, Chen HM, Xiong SM, Chen B, Shi JY, Wang YY, Wang JH, Chen Y, Li JM, Gu LJ, Tang JY, Shen ZX, Gu BW, Zhao WL, Chen Z, Chen SJ.
Leukemia. 2009 Sep;23(9):1598-604.

The in vivo bone formation by mesenchymal stem cells in zein scaffolds.
Tu J, Wang H, Li H, Dai K, Wang J, Zhang X.
Biomaterials. 2009 Sep;30(26):4369-76.

In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration.
Huang Y, Jin X, Zhang X, Sun H, Tu J, Tang T, Chang J, Dai K.
Biomaterials. 2009 Oct;30(28):5041-8.

MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins.
Tang Y, Luo X, Cui H, Ni X, Yuan M, Guo Y, Huang X, Zhou H, de Vries N, Tak PP, Chen S, Shen N.
Arthritis Rheum. 2009 Apr;60(4):1065-75.

Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.
Li L, Zhang X, Yang D, Luo G, Chen S, Le W.
Neurobiol Aging. 2009 Jul;30(7):1091-8.
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