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Key Lab of Stem Cell Biology
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Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cells.
Gu ZM, Wu YL, Zhou MY, Liu CX, Xu HZ, Yan H, Zhao Y, Huang Y, Sun HD, Chen GQ.
Blood. 2010 Dec 9;116(24):5289-97.

Nonsense-mediated decaytargets have multiple sequence-related features that can inhibit translation.
Zhang Z, Li Z, Hu L, Zhu Y, Xu H, Liu Y, Chen X, Yi X, Kong X, Hurst LD.
Mol Syst Biol. 2010 Dec 14;6:442.

Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.
Zhu S, Pan W, Shi P, Gao H, Zhao F, Song X, Liu Y, Zhao L, Li X, Shi Y, Qian Y.
J Exp Med. 2010 Nov 22;207(12):2647-62.

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis.
Chen G, Zhang X, Li R, Fang L, Niu X, Zheng Y, He D, Xu R, Zhang JZ.
Arthritis Rheum. 2010 Oct;62(10):2900-8.

A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer.
Yan F, Cao XX, Jiang HX, Zhao XL, Wang JY, Lin YH, Liu QL, Zhang C, Jiang B, Guo F.
J Med Chem. 2010 Aug 12;53(15):5502-10.

Regulation of Th1 and Th17 cell differentiation and amelioration of experimental autoimmune encephalomyelitis by natural product compound berberine.
Qin X, Guo BT, Wan B, Fang L, Lu L, Wu L, Zang YQ, Zhang JZ.
J Immunol. 2010 Aug 1;185(3):1855-63.

Transcriptome Analysis of Early Organogenesis in Human Embryos.
Fang H, Yang Y, Li C, Fu S, Yang Z, Jin G, Wang K, Zhang J, Jin Y.
Dev Cell. 2010 Jul 20;19(1):174-184.

Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy.
Li Q, Song XW, Zou J, Wang GK, Kremneva E, Li XQ, Zhu N, Sun T, Lappalainen P, Yuan WJ, Qin YW, Jing Q.
J Cell Sci. 2010 Jul 15;123(Pt 14):2444-52.

Type 3 inositol 1,4,5-trisphosphate receptor negatively regulates apoptosis during mouse embryonic stem cell differentiation.
Liang J, Wang YJ, Tang Y, Cao N, Wang J, Yang HT.
Cell Death Differ. 2010 Jul;17(7):1141-54.

An evolutionarily conserved PTEN-C/EBP{alpha}-CTNNA1 axis controls myeloid development and transformation.
Fu CT, Zhu KY, Mi JQ, Liu YF, Murray ST, Fu YF, Ren CG, Dong ZW, Liu YJ, Dong M, Jin Y, Chen Y, Deng M, Zhang W, Chen B, Breslin P, Chen SJ, Chen Z, Becker MW, Zhu J, Zhang JW, Liu TX.
Blood. 2010 Jun 10;115(23):4715-24.

Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair.
Shi Y, Hu G, Su J, Li W, Chen Q, Shou P, Xu C, Chen X, Huang Y, Zhu Z, Huang X, Han X, Xie N, Ren G.
Cell Res. 2010 May;20(5):510-8.

Length of the ORF, position of the first AUG and the Kozak motif are important factors in potential dual-coding transcripts.
Xu H, Wang P, Fu Y, Zheng Y, Tang Q, Si L, You J, Zhang Z, Zhu Y, Zhou L, Wei Z, Lin B, Hu L, Kong X.
Cell Res. 2010 Apr;20(4):445-57.

Down-regulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.
Shen SM, Yu Y, Wu YL, Cheng JK, Wang LS, Chen GQ.
Carcinogenesis. 2010 Mar;31(3):419-26.

Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner.
Liao B, Jin Y.
Cell Res. 2010 Mar;20(3):332-44.

The downregulation of onzin expression by PKCε-ERK2 signaling and its potential role in AML cell differentiation.
Wu SF, Huang Y, Hou JK, Yuan TT, Zhou CX, Zhang J, Chen GQ.
Leukemia. 2010 Mar;24(3):544-51.

Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish.
Yuan H, Zhou J, Deng M, Liu X, Bras ML, The HD, Chen SJ, Chen Z, Liu TX, Zhu J.
Cell Res. 2010 Feb;20(2):185-96.

Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation.
Li L, Sun L, Gao F, Jiang J, Yang Y, Li C, Gu J, Wei Z, Yang A, Lu R, Ma Y, Tang F, Won Kwon S, Zhao Y, Li J, Jin Y.
Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1402-7.

Lysine Acetylation Regulates Bruton's Tyrosine Kinase in B Cell Activation.
Liu Z, Mai A, Sun J.
J Immunol. 2010 Jan 1;184(1):244-54.

Perivascular Adipose Tissue-Derived Complement 3 Is Required for Adventitial Fibroblast Functions and Adventitial Remodeling in Deoxycorticosterone Acetate-Salt-Hypertensive Rats.
Ruan CC, Chen QZ, Chen J, Guo SJ, Li XD, Zhu DL, Gao PJ.
Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2568-74.

miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells.
Zhou H, Huang X, Cui H, Luo X, Tang Y, Chen S, Wu L, Shen N.
Blood. 2010 Dec 23;116(26):5885-94.

MicroRNA-125a contributes to elevated inflammatory chemokine RANTES via targeting KLF13 in systemic lupus erythematosus.
Zhao X, Tang Y, Qu B, Cui H, Wang S, Wang L, Luo X, Huang X, Li J, Chen S, Shen N.
Arthritis Rheum. 2010 Nov;62(11):3425-35.

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus.
Shen N, Fu Q, Deng Y, Qian X, Zhao J, Kaufman KM, Wu YL, Yu CY, Tang Y, Chen JY, Yang W, Wong M, Kawasaki A, Tsuchiya N, Sumida T, Kawaguchi Y, Howe HS, Mok MY, Bang SY, Liu FL, Chang DM, Takasaki Y, Hashimoto H, Harley JB, Guthridge JM, Grossman JM, Cantor RM, Song YW, Bae SC, Chen S, Hahn BH, Lau YL, Tsao BP.
Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15838-43.

MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.
Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo X, Li J, Zhou H, Tang Y, Shen N.
J Immunol. 2010 Jun 15;184(12):6773-81.

Evidence for microRNA-mediated regulation in rheumatic diseases.
Luo X, Tsai LM, Shen N, Yu D.
Ann Rheum Dis. 2010 Jan;69 Suppl 1: i30-36.

18β-glycyrrhetinic acid ameliorated Propionibacterium acnes-induced acute liver injury through inhibition of MIP-1α.
Xiao Y, Xu J, Mao C, Jin M, Wu Q, Zou J, Gu Q, Zhang Y, Zhang Y.
J Biol Chem. 2010 Jan 8;285(2):1128-37.
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