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Key Lab of Stem Cell Biology
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Alternative splicing at GYNNGY 5' splice sites: more noise, less regulation.
Wang M, Zhang P, Shu Y, Yuan F, Zhang Y, Zhou Y, Jiang M, Zhu Y, Hu L, Kong X, Zhang Z.
Nucleic Acids Res. 2014 Dec 16;42(22):13969-80.

Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells.
Yang J, Tang Y, Liu H, Guo F, Ni J, Le W.
BMC Biol. 2014 Nov 19;12(1):95.

Foxd3 suppresses NFAT-mediated differentiation to maintain self-renewal of embryonic stem cells.
Zhu L, Zhang S, Jin Y.
EMBO Rep. 2014 Dec;15(12):1286-96.

Degradation of cardiac myosin light chain kinase by matrix metalloproteinase-2 contributes to myocardial contractile dysfunction during ischemia/reperfusion.
Gao L, Zheng YJ, Gu SS, Tan JL, Paul C, Wang YG, Yang HT.
J Mol Cell Cardiol. 2014 Dec;77:102-112.

p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation.
Huang Y, Yu P, Li W, Ren G, Roberts AI, Cao W, Zhang X, Su J, Chen X, Chen Q, Shou P, Xu C, Du L, Lin L, Xie N, Zhang L, Wang Y, Shi Y.
Oncogene. 2014 Jul 17;33(29):3830-8.

Interferon-α-secreting mesenchymal stem cells exert potent antitumor effect in vivo.
Xu C, Lin L, Cao G, Chen Q, Shou P, Huang Y, Han Y, Wang Y, Shi Y.
Oncogene. 2014 Oct 16;33(42):5047-52.

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications.
Wang Y, Chen X, Cao W, Shi Y.
Nat Immunol. 2014 Oct 20;15(11):1009-1016.

Interleukin-17 Enhances Immunosuppression by Mesenchymal Stem Cells.
Han X, Yang Q, Lin L, Xu C, Zheng C, Chen X, Han Y, Li M, Cao W, Cao K, Chen Q, Xu G, Zhang Y, Zhang J, Schneider RJ, Qian Y, Wang Y, Brewer G, Shi Y.
Cell Death Differ. 2014 Nov;21(11):1758-68.

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Dang S, Xu H, Xu C, Cai W, Li Q, Cheng Y, Jin M, Wang RX, Peng Y, Zhang Y, Wu C, He X, Wan B, Zhang Y.
Autophagy. 2014 Jul 1;10(7):1301-15.

Concentration-dependent wrestling between detrimental and protective effects of H2O2 during myocardial ischemia/reperfusion.
Wang ZH, Liu JL, Wu L, Yu Z, Yang HT.
Cell Death Dis. 2014 Jun 19;5:e1297.

A microRNA 221- and 222-mediated feedback loop, via PDLIM2, maintains constitutive activation of NFκB and STAT3 in colorectal cancer cells.
Liu S, Sun X, Wang M, Hou Y, Zhan Y, Jiang Y, Liu Z, Cao X, Chen P, Liu Z, Chen X, Tao Y, Xu C, Mao J, Cheng C, Li C, Hu Y, Wang L, Chin YE, Shi Y, Siebenlist U, Zhang X.
Gastroenterology. 2014 Oct;147(4):847-859.e11.

DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis.
Wang Y, Lei R, Zhuang X, Zhang N, Pan H, Li G, Hu J, Pan X, Tao Q, Fu D, Xiao J, Chin YE, Kang Y, Yang Q, Hu G.
J Clin Invest. 2014 Apr 1;124(4):1646-59.

The interaction between mesenchymal stem cells and steroids during inflammation.
Chen X, Gan Y, Li W, Su J, Zhang Y, Huang Y, Roberts AI, Han Y, Li J, Wang Y, Shi Y.
Cell Death Dis. 2014 Jan 23;5:e1009.

TGF-β promotes immune responses in the presence of mesenchymal stem cells.
Xu C, Yu P, Han X, Du L, Gan J, Wang Y, Shi Y.
J Immunol. 2014 Jan 1;192(1):103-9.

Alterations in the microbiota drive Interleukin-17C production from intestinal epithelial cells to promote tumorigenesis.
Song X, Gao H, Lin Y, Yao Y, Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, Qian Y.
Immunity. 2014 Jan 16;40(1):140-52.

Human superoxide dismutase 1 overexpression in motor neurons of Caenorhabditis elegans causes axon guidance defect and neurodegeneration.
Li J, Li T, Zhang X, Tang Y, Yang J, Le W.
Neurobiol Aging. 2014 Apr;35(4):837-46.

An Osteopontin-Integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells.
Chen Q, Shou P, Zhang L, Xu C, Zheng C, Han Y, Li W, Huang Y, Zhang X, Shao C, Roberts AI, Rabson AB, Ren G, Zhang Y, Wang Y, Denhardt DT, Shi Y.
Stem Cells. 2014 Feb;32(2):327-37.

Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis.
Lei R, Tang J, Zhuang X, Deng R, Li G, Yu J, Liang Y, Xiao J, Wang HY, Yang Q, Hu G.
Oncogene. 2014 Mar 6;33(10):1287-96.

Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson's disease.
Tang Y, Li T, Li J, Yang J, Liu H, Zhang XJ, Le W.
Cell Death Differ. 2014 Mar;21(3):369-80.

Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species.
Su J, Chen X, Huang Y, Li W, Li J, Cao K, Cao G, Zhang L, Li F, Roberts AI, Kang H, Yu P, Ren G, Ji W, Wang Y, Shi Y.
Cell Death Differ. 2014 Mar;21(3):388-96.

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